Table 1.

Characteristics of lung cancer cases and controls

CharacteristicCases (N = 1,553)Controls (N = 1,730)P *
Male, n (%)818 (52.7)894 (51.7)0.57
Age (y), n (%)0.04
    <50266 (17.1)212 (12.3)
    50–59362 (23.3)441 (25.5)
    60–64235 (15.1)417 (24.1)
    65–69258 (16.6)353 (20.4)
    70+432 (27.8)307 (17.8)
Age (y), median6362
Smoking status, n (%)0.07
    Current626 (40.3)659 (38.1)
    Former653 (42.1)795 (46.0)
    Never274 (17.6)276 (16.0)
Pack-years, median (IQR), among ever smokers46 (30-68)40 (26-60)<0.0001
History of emphysema, n (%)288 (18.5)145 (8.4)<0.0001
History of hay fever, n (%)265 (17.1)383 (22.1)0.0003
Family history of lung cancer, n (%)312 (20.1)260 (15.0)0.0002
Lung cancer histology, n (%)
    Adenocarcinoma849 (54.7)
    Squamous cell carcinoma326 (21.0)
    Other/unspecified non–small cell carcinoma263 (16.9)
    Small cell carcinoma95 (6.1)
    Other/unspecified20 (1.3)
Lung cancer stage, n (%)
    I318 (22.1)
    II108 (7.5)
    III472 (32.8)
    IV440 (30.6)
    Unknown/missing102 (7.1)
  • Abbreviation: IQR, interquartile range.

  • * P values are derived by χ test, except for age and pack-years, where the Wilcoxon rank sum test was used.

  • Stage is limited to non–small cell carcinomas.