Table 1.

CpG island hypermethylation distribution of the MeDIP-identified candidate genes

GenesColorectal cancer cell linesColorectal primary tumorsAdenomasNormal colon
SCNN1B88% (7/8)20% (11/56)13% (4/30)0% (0/10)
RASGRF238% (3/8)45% (29/65)35% (12/34)0% (0/10)
BHLHB9 *42% (3/7)33% (18/54)33% (9/27)0% (0/7)
HOXD113% (1/8)4% (2/52)0% (0/33)0% (0/10)
  • * For BHLHB9, located in the X-chromosome, only samples from male donors were included.