Table 1.

IC50 of nelfinavir for colon cancer and melanoma cell lines

Colon cancer cell linesIC50 (μmol/L)Melanoma cell linesIC50 (μmol/L)
Colo2056.61205LU4.0
HCT-11610.5A37511.0
HT-298.6C81616.5
KM12L49.0NIH12865.0
SW48030.0WM355.5
SW62015.0WM1156.7
  • NOTE: Cells were treated with varying amounts of nelfinavir for 48 h. Viable cells were counted using trypan blue staining. Cell counting was done in triplicate. IC50 was estimated by curve fitting.