Table 1.

Prevalence and histologic characteristics of follicular alterations in Pten+/− and PtenL/L;TPO-Cre mice

GenotypeSexNo.Age (wk)Normal (%)Focal hyperplasia (%)Nodular hyperplasia (%)Adenoma (%)
Pten+/−Male1528–6413.346.7400
Female1426–5614.335.7500
PtenL/L;TPO-CreMale833–4400100 *0
Female734–450028.6 *71.4 *
  • * In a context of diffuse goiter.