Table 2.

Differential expression of miRNAs in neuroblastoma subtypes

miRNAChromosome mapMNA/hyperdiploid *11q−/hyperdiploid *MNA/11q− *
let-7a22q13/9q22/11q242.4×
let-7b22q133.99×
miR-27b9q22.320.48×0.36×
miR-30b8q24.220.44×
miR-30c1p34.2/6q130.44×
miR-30e1p34.20.24×
miR-9213q31.3/Xq26.23.64×
miR-10710q23.310.32×
miR-1297q32.1/11p11.20.08×
miR-1371p21.30.19×
miR-14112p13.312.09×0.26×
miR-146a5q33.30.25×
miR-1492q37.30.26×
miR-15019q13.330.34×
miR-181a9q33.32.4×3.75×
miR-181b9q33.3/1q31.34.05×8.85×
miR-18415q25.12.2×0.42×
miR-1861q31.10.38×
miR-18718q12.22.92×
miR-1899q22.320.27×0.39×
miR-19015q22.20.10×
miR-200a1p36.330.26×
miR-200c12p13.310.45×
miR-2162p16.10.27×
miR-30117q23.20.37×
miR-302a4q250.39×
miR-32314q32.310.21×0.27×
miR-324-5p17p13.10.22×
miR-32611q13.40.35×0.62×
miR-33019q13.320.29×
miR-33112q220.40×0.63×
miR-3357q32.20.45×
  • * Fold difference in mean expression between the tumor subtypes being compared (i.e., MNA versus hyperdiploid, 11q− versus hyperdiploid, and MNA versus 11q−. P values obtained from one-way ANOVA ranged from <0.01 to <0.05, with 31 comparisons having P values of <0.01 and 10 comparisons having P values between 0.01 and <0.05. All comparisons were statistically significant when the Tukey-Kramer correction for multiple comparisons was applied.