Table 1.

Cancer cell lines used in this study with IC₅₀ to dasatinib, sensitivity classification by IC₅₀, and predicted sensitivity by the six-gene predictor

Cell line	IC₅₀ (μmol/L)	Sensitivity classification based on IC₅₀	Sensitivity prediction by six-gene predictor
(A) Training set of breast cancer cell lines
MDA-MB-157	0.0055	Sensitive
MDA-MB-231	0.0095	Sensitive
HCC1954	0.0242	Sensitive
HCC70	0.0337	Sensitive
BT-20	0.1652	Sensitive
HCC1806	0.2194	Sensitive
HS578T	0.6472	Sensitive
HCC1419	2.5093	Resistant
SK-BR-3	2.7534	Resistant
AU-565	5.2399	Resistant
HCC38	6.6327	Resistant
BT-474	6.7375	Resistant
MDA-MB-468	7.1258	Resistant
HCC1428	7.2926	Resistant
MDA-MB-435S	7.7800	Resistant
H3396	8.1950	Resistant
BT-549	9.0576	Resistant
ZR-75-30	9.2632	Resistant
MCF7	>9.524	Resistant
MCF7/Her2	>9.524	Resistant
MDA-MB-436	>9.524	Resistant
ZR-75-1	>9.524	Resistant
MDA-MB-453	>9.524	Resistant

(B) Testing set of breast cancer cell lines
HCC1143	0.0235	Sensitive	Sensitive
MBA-MB-415	0.0394	Sensitive	Resistant
HCC1937	0.0706	Sensitive	Sensitive
HCC1395	0.0818	Sensitive	Sensitive
UACC-812	1.2158	Resistant	Resistant
MDA-MB-361	1.4383	Resistant	Resistant
HCC1187	1.5793	Resistant	Resistant
DU4475	2.6329	Resistant	Resistant
HCC2157	5.4530	Resistant	Resistant
HCC202	5.5841	Resistant	Resistant
HCC2218	8.6515	Resistant	Resistant
HCC1500	>8.926	Resistant	Resistant

(C) Testing set of lung cancer cell lines
SK-LU-1	0.0137	Sensitive	Sensitive
L2987	0.0371	Sensitive	Sensitive
H226	0.0583	Sensitive	Sensitive
H838	0.0724	Sensitive	Sensitive
H661	0.1231	Sensitive	Sensitive
NCI-H596	0.1238	Sensitive	Sensitive
H441	0.1411	Sensitive	Sensitive
SK-MES-1	0.1512	Sensitive	Sensitive
H522	0.2151	Sensitive	Resistant
SW1271	0.2424	Sensitive	Sensitive
SW900	0.5074	Sensitive	Sensitive
H2347	1.0246	Resistant	Resistant
H1155	1.0246	Resistant	Resistant
H23	1.0246	Resistant	Sensitive
A-427	>1.025	Resistant	Resistant
ChaGo-K-1	>1.025	Resistant	Sensitive
A549	>1.025	Resistant	Sensitive
Calu-6	>1.025	Resistant	Resistant
DMS114	>1.025	Resistant	Resistant
DMS53	>1.025	Resistant	Resistant
H157	>1.025	Resistant	Resistant
LX-1	>1.025	Resistant	Resistant
SHP-77	>1.025	Resistant	Resistant