Table 1.

Characteristics of PC cases and population controls

CharacteristicFamilial PC, * N = 435Sporadic PC, N = 491Aggressive PC, N = 195Controls, N = 545
Age, median (range)66 (45–84)65 (46–79)65 (40–86)64 (44–91)
Age, quartiles
    40–6077 (17.7)116 (23.6)63 (32.3)212 (38.9)
    61–65117 (26.9)149 (30.4)40 (20.5)104 (19.1)
    66–70131 (30.1)167 (34.0)48 (24.6)90 (16.5)
    71–91110 (25.3)59 (12.0)44 (22.6)139 (25.5)
Body mass index (kg/m2)
    <28288 (66.5)308 (62.7)96 (49.5)225 (41.3)
    ≥28145 (33.5)183 (37.3)98 (50.5)320 (58.7)
    Missing2010
Prostate-specific antigen
    <440 (12.0)91 (22.9)26 (18.3)503 (92.3)
    4–9.9153 (46.0)173 (43.6)68 (47.9)39 (7.2)
    10–19.968 (20.4)72 (18.1)27 (19.0)3 (0.6)
    ≥2072 (21.6)61 (15.4)21 (14.8)0 (0.0)
    Unknown10294530
Gleason score
    <7249 (69.8)263 (67.4)0
    781 (22.7)108 (27.7)0
    ≥827 (7.6)19 (4.9)195 (100.0)
    Unknown781010
Nodal status
    +52 (12.2)57 (11.6)27 (15.7)
    −376 (87.9)434 (88.4)145 (84.3)
    Unknown7023
Stage
    T1/T2270 (71.8)287 (67.4)59 (40.7)
    T3/T4106 (28.2)139 (32.6)86 (59.3)
    Unknown596550
  • * One hundred and seventy-seven unique families.

  • Defined as age at diagnosis for familial PC and sporadic PC groups, and age at last follow-up for controls.