Table 3.

Association of alleles on chromosome 8q24 with sporadic, familial, and aggressive PC

ComparisonMarkerAlleleAllele frequencyOR (95% CI) *P
PC CasesControls
Sporadic PC vs. controlsDG8S737−80.0570.0571.05 (0.71–1.57)0.96
DG8S737−100.0240.0211.11 (0.61–2.04)0.73
rs1447295A0.1190.1031.16 (0.85–1.58)0.25
Familial PC vs. controlsDG8S737−80.0880.0571.68 (1.09–2.60)0.031
DG8S737−100.0320.0211.55 (0.80–3.02)0.21
rs1447295A0.1670.1031.93 (1.37–2.72)0.0004
Aggressive PC vs. controlsDG8S737−80.0670.0571.23 (0.73–2.05)0.48
DG8S737−100.0590.0212.85 (1.52–5.36)0.0004
rs1447295A0.1720.1031.87 (1.28–2.74)0.0005
  • * OR comparing carriers of the indicated allele to noncarriers.