Table 1.

Association of overexpression of Pak1 mRNA with clinicopathologic features in human HCCs

Clinicopathologic featuresPak1 expression
Not overexpressedOverexpressedP
Venous invasionAbsent870.002
Present118
Tumor microsatelliteAbsent9170.209
Present419
Liver invasionAbsent10170.086
Present217
Cellular differentiation (Edmondson's grading)I–II84<0.001
III–V119
Tumor size (cm)≤5560.123
>5417
Tumor stageI–II740.003
III–V218
Tumor encapsulationAbsent7250.331
Present611
Disease-free survival (mo)MedianNot reached6.5 ± 6.40.022
Mean43.1 ± 7.718.3 ± 4.2
Overall survival (mo)MedianNot reached29.8 ± 12.60.063
Mean49.2 ± 5.930.8 ± 4.9