Table 1.

Estimated tumor and normal organ absorbed doses per 120 μCi 213Bi-7.16.4 in rat HER-2/neu--expressing subcutaneous and metastatic tumor model

α Dose (Gy)β Dose (Gy)
Blood6.200.49
Heart1.100.09
Lung1.450.11
Liver2.240.18
Spleen1.970.16
Kidney1.680.13
Stomach0.380.03
Left femur0.470.04
Right femur0.480.04
Subcutaneous tumor2.440.19
Micrometastasis *4.430.35
  • * Dose to micrometastases was calculated using the biodistribution data shown in Fig. 2B.