Table 1.

MiRNAs dysregulated in stage II colon cancer

MiRNARegulation *Fold (log 2)
Normal vs MSI comparison
    hsa-miR-145Down−1.9
    hsa-miR-455Down−1.3
    hsa-miR-484Down−1.2
    hsa-miR-101Down−1.0
    hsa-miR-492Up1.2
    hsa-miR-20aUp1.1
    hsa-miR-432*Up1.1
    hsa-miR-21Up1.0
Normal vs MSS comparison
    hsa-miR-142-3pDown−2.4
    hsa-miR-212Down−2.3
    hsa-miR-146bDown−1.9
    hsa-miR-217Down−1.7
    hsa-miR-20aUp1.6
    hsa-miR-510Up1.5
    hsa-miR-92Up1.3
    hsa-miR-513Up1.2
MSS vs MSI comparison
    hsa-miR-212Down−2.3
    hsa-miR-142-3pDown−2.1
    hsa-miR-144Down−1.5
    hsa-miR-151Down−1.4
MiRNAs dysregulated in both MSI and MSS
    hsa-miR-145Down−1.7
    hsa-miR-455Down−1.4
    hsa-miR-484Down−1.2
    hsa-miR-101Down−1.1
    hsa-miR-20aUp1.4
    hsa-miR-510Up1.3
    hsa-miR-92Up1.0
    hsa-miR-513Up1.0
Recurrence vs nonrecurrence comparison (MSS only)
    hsa-let-7dUp0.7
    hsa-let-7bUp0.7
    hsa-miR-126Up0.5
    hsa-miR-1Up0.5
    hsa-miR-320Down−1.1
    hsa-miR-498Down−0.7
    hsa-miR-492Down−0.7
    hsa-miR-526cDown−0.7
  • * Up- or down-regulation is stated as miRNA expression in cancer relative to normal, recurrence relative to nonrecurrence, or MSS relative to MSI.

  • Median log2 fold change between the two groups compared.