Table 2.

Major allele frequencies and FBAT results (n = 403 families)

dbSNP ID	Base pair position	Gene	Location	Alleles major>minor	Major allele frequency		FBAT *
dbSNP ID	Base pair position	Gene	Location	Alleles major>minor	Affected (n = 542)	Unaffected (n = 473)	n^†	Z score	P
rs4430796	33,172,153	TCF2	Intron 2	A>G	0.59	0.53	210	2.73	0.006
rs7501939	33,175,269	TCF2	Intron 1	C>T	0.67	0.62	198	2.64	0.008
rs1859962	66,620,384	—	Intergenic	G>T	0.55	0.51	208	1.86	0.063

NOTE: rs4430796 and rs7501939 are in strong linkage disequilibrium (r² = 0.68).
↵* Based on the combined sample of men with and without prostate cancer and an additive genetic model for the major allele.
↵† Number of informative families.