Table 3.

Comparison of ORs for 17q SNPs tested in the University of Michigan, Gudmundsson et al., and the Cancer Genetic Markers of Susceptibility studies

dbSNP ID	Risk allele	UM *		Gudmundsson et al. ^†		CGEMS ^‡
dbSNP ID	Risk allele	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
rs4430796	A	1.40 (1.09–1.81)	0.009	1.20 (1.11–1.31)	<0.001	1.17 (1.04–1.31)	0.009
rs7501939	C	1.44 (1.10–1.89)	0.008	1.17 (1.08–1.27)	<0.001	1.19 (1.06–1.34)	0.004
rs1859962	G	1.21 (0.94–1.56)	0.132	1.16 (1.07–1.26)	<0.001	1.19 (1.06–1.34)	0.003

NOTE: ORs were computed under an additive genetic model.

Abbreviations: UM, University of Michigan; CGEMS, Cancer Genetic Markers of Susceptibility.
↵* Before conducting the conditional logistic regression analyses, we excluded 38 men (from 10 families) who were not brothers of the index case, resulting in a reduced sample size of 977 men and 604 discordant sibling pairs.
↵† Logistic regression as reported by Gudmundsson et al. ( 7), all samples combined (1,501 cases and 11,289 controls).
↵‡ Logistic regression, unadjusted for covariates (1,155 cases and 1,106 controls).