Characteristics of patients
Diagnosis | Subgroup | N | % of total with abnormal SNP-A | % of total with UPD | % of those with abnormal SNP-A having UPD | |
---|---|---|---|---|---|---|
Total (n = 301) | MDS (n = 140) | RA/RARS/RCMD/5q | 67 | 63 | 18 | 29 |
RAEB I/II | 28 | 79 | 14 | 18 | ||
Secondary AML | 45 | 67 | 20 | 30 | ||
MDS/MPD (n = 81) | MDS/MPDu | 29 | 66 | 34 | 53 | |
CMML | 27 | 74 | 41 | 55 | ||
Secondary AML * | 25 | 88 | 60 | 68 | ||
MPD (n = 14) | N/a | 7 | 100 | 57 | 57 | |
Secondary AML | 7 | 86 | 57 | 67 | ||
pAML (n = 66) | N/a | 66 | 56 | 24 | 43 |
NOTE: Samples from 116 healthy individuals were used as controls.
Abbreviations: N/a, not applicable; pAML, primary AML.
↵* Includes patients who evolved to AML from both MDS/MPDu and CMML.