Table 1.

Incidence of metastases produced by the HCT116 sh control and shZEB1 cell clones after tail vein or intrasplenic injection to nude mice

HCT116 cloneInjection procedurePrimary tumorsMetastases
No. of miceAverage size (mm)No. of miceTotal no.LocationAverage size (mm)
sh control C1Tail vein4/610Lung1.2
Intrasplenic5/58.14/514Liver (11)1.8
Pancreas (3)0.9
shZEB1 Z4Tail vein1/61Lung0.5
Intrasplenic5/57.90/60
  • NOTE: P < 0.01 (for metastasis, number and size).