Table 2.

Differential expression of immunohistochemical markers between the epithelial and mesenchymal components of breast carcinosarcomas (n = 12)

Immunohistochemical markerEpithelial (carcinoma)Mesenchymal (sarcoma)
SPARC-positive5 (42%)10 (83%)
Vimentin-positive10 (83%)12 (100%)
E-cadherin–positive12 (100%)0 (0%)
P-cadherin–positive11 (92%)0 (0%)
Cadherin-11–positive2 (17%)10 (83%)
β-catenin:
    Membrane-conserved10 (83%)2 (17%)
    Membrane-reduced2 (17%)7 (58%)
    Cytoplasmic/nuclear0 (0%)3 (25%)
p120:
    Membrane-conserved10 (83%)2 (17%)
    Membrane-reduced2 (17%)2 (17%)
    Cytoplasmic/nuclear0 (0%)8 (67%)