Table 2.

Mutation patterns identified for the EGFR, KRAS, and PI3KCA genes and gene amplifications in EGFR and HER2 in pancreatic cancer tumors

CasesEGFRKRASBRAFPIK3CAEGFR FISHHER2 FISH
Learning set
    198wtmutwtwt11
    410wtwtwtmut55
    286wtmutwtwt22
    140wtmutwtwt56
    163wtmutwtwt44
    287wtwtwtwt55
    253wtmutwtwt44
    194wtmutwtwt42
    265wtmutwtwt24
    215wtmutwtwt54
Validation set
    219wtmutwtwt23
    294wtmutwtwt44
    281wtmutwtwt56
    247wtmutwtwt55
    185wtmutwtwt54
    159wtmutwtwt41
    354wtwtwtwt22
  • NOTE: Sensitive cases are shown in bold.

  • Abbreviations: wt, wild type; mut, mutant.