Mutation patterns identified for the EGFR, KRAS, and PI3KCA genes and gene amplifications in EGFR and HER2 in pancreatic cancer tumors
Cases | EGFR | KRAS | BRAF | PIK3CA | EGFR FISH | HER2 FISH |
---|---|---|---|---|---|---|
Learning set | ||||||
198 | wt | mut | wt | wt | 1 | 1 |
410 | wt | wt | wt | mut | 5 | 5 |
286 | wt | mut | wt | wt | 2 | 2 |
140 | wt | mut | wt | wt | 5 | 6 |
163 | wt | mut | wt | wt | 4 | 4 |
287 | wt | wt | wt | wt | 5 | 5 |
253 | wt | mut | wt | wt | 4 | 4 |
194 | wt | mut | wt | wt | 4 | 2 |
265 | wt | mut | wt | wt | 2 | 4 |
215 | wt | mut | wt | wt | 5 | 4 |
Validation set | ||||||
219 | wt | mut | wt | wt | 2 | 3 |
294 | wt | mut | wt | wt | 4 | 4 |
281 | wt | mut | wt | wt | 5 | 6 |
247 | wt | mut | wt | wt | 5 | 5 |
185 | wt | mut | wt | wt | 5 | 4 |
159 | wt | mut | wt | wt | 4 | 1 |
354 | wt | wt | wt | wt | 2 | 2 |
NOTE: Sensitive cases are shown in bold.
Abbreviations: wt, wild type; mut, mutant.