Table 1.

Differential expression of let-7 and miR-200 in gemcitabine-sensitive and gemcitabine-resistant pancreatic cancer cells treated with B-DIM or G2535 tested by miRNA array

miRNAGemcitabine-sensitive
L3.6plColo357
ControlB-DIMG2535ControlB-DIMG2535
hsa-let-7a15,048.016,837.022,667.814,213.115,750.521,823.0
hsa-let-7b8,118.19,753.412,240.17,554.49,243.412,668.5
hsa-let-7c11,295.613,596.517,622.99,387.211,167.214,446.9
hsa-let-7d10,132.512,494.815,597.59,237.110,822.315,712.6
hsa-let-7e3,973.37,079.58,637.52,718.03,788.03,505.7
hsa-let-7f11,602.413,645.917,989.510,789.112,277.517,104.3
hsa-miR-200b4,510.14,520.45,425.15,202.56,822.24,132.7
hsa-miR-200c11,078.79,360.914,072.411,949.813,942.618,571.2
miRNAGemcitabine-resistant
MiaPaCa2Panc-1
ControlB-DIMG2535ControlB-DIMG2535
hsa-let-7a7,535.66,700.98,243.311,009.411,333.514,812.4
hsa-let-7b1,490.01,316.92,635.53,582.83,862.03,895.1
hsa-let-7c3,811.33,265.64,998.74,242.25,799.98,028.4
hsa-let-7d4,251.83,806.05,806.16,190.56,171.110,086.7
hsa-let-7e1,728.62,082.53,963.92,442.72,277.64,016.5
hsa-let-7f5,649.45,375.57,496.47,771.17,679.712,454.1
hsa-miR-200b5.937.0411.603.964.874.79
hsa-miR-200c7.578.026.618.5111.1015.54