Table 1.

Association (in combined analysis of UK-GWA study phases 1 and 2) between 15q25.1 SNPs (rs938682, rs12914385, and rs8042374) and lung cancer, with and without adjustment for a second variant

rs938682rs12914385rs8042374
PtrendOR (95% CI)PtrendOR (95% CI)PtrendOR (95% CI)
Unadjusted1.45 × 10−140.75 (0.70–0.81)4.79 × 10−161.29 (1.21–1.37)5.82 × 10−150.75 (0.70–0.80)
Adjusted for
rs9386821.00 × 10−71.20 (1.12–1.28)0.910.94 (0.36–2.48)
rs129143854.17 × 10−60.83 (0.76–0.90)2.13 × 10−60.82 (0.76–0.89)
rs80423740.630.79 (0.30–2.08)1.81 × 10−71.20 (1.12–1.28)