Table 3.

Adjusted relative risk of TGCTs by quartile of lipid-adjusted levels of serum organochlorines in the STEED study

ng/g lipidControlsAll TGCTSeminomaNonseminoma
nnOR * (95% CI)nOR * (95% CI)nOR * (95% CI)
PCB-99
    Q1<9.95904961.001991.002971.00
    Q29.9–12.5109680.72 (0.52–1.02)330.78 (0.50–1.22)350.68 (0.44–1.04)
    Q312.6–18.3106900.89 (0.64–1.24)400.86 (0.56–1.34)490.91 (0.61–1.35)
    Q4>18.3107810.80 (0.57–1.13)410.80 (0.51–1.25)400.76 (0.50–1.17)
    Ptrend0.140.260.16
PCB-101
    Q1<4.75704691.002001.002681.00
    Q24.7–6.1114820.93 (0.67–1.27)330.82 (0.53–1.27)490.99 (0.68–1.45)
    Q36.2–8.9114931.06 (0.78–1.44)391.06 (0.70–1.61)541.12 (0.77–1.62)
    Q4>8.9114901.01 (0.74–1.38)401.12 (0.74–1.70)500.91 (0.62–1.33)
    Ptrend0.920.640.80
PCB-118
    Q1<7.22652661.00821.001841.00
    Q27.2–10.52161710.71 (0.53–0.94)800.97 (0.66–1.44)910.59 (0.42–0.82)
    Q310.6–15.62161510.60 (0.45–0.81)760.86 (0.57–1.28)740.47 (0.33–0.68)
    Q4>15.62161480.55 (0.40–0.76)750.72 (0.47–1.12)730.45 (0.31–0.66)
    Ptrend0.00070.100.0001
PCB-138
    Q1<15.62362421.00731.001691.00
    Q215.6–24.52271680.65 (0.48–0.88)680.78 (0.51–1.20)1000.61 (0.43–0.86)
    Q324.6–37.72251620.54 (0.39–0.75)880.78 (0.50–1.22)740.41 (0.28–0.61)
    Q4>37.72251640.46 (0.32–0.66)840.52 (0.31–0.86)790.42 (0.27–0.65)
    Ptrend0.00010.010.0002
PCB-153
    Q1<23.42312431.00741.001691.00
    Q223.4–37.22271580.61 (0.45–0.82)610.71 (0.46–1.09)970.58 (0.41–0.82)
    Q337.3–56.32291660.53 (0.38–0.73)850.69 (0.44–1.09)810.44 (0.30–0.65)
    Q4>56.32261690.45 (0.31–0.66)930.52 (0.31–0.87)750.40 (0.26–0.63)
    Ptrend0.00030.020.0002
PCB-156
    Q1<5.34774221.001481.002741.00
    Q25.3–6.9145980.66 (0.48–0.90)440.68 (0.45–1.05)540.63 (0.43–0.92)
    Q37.0–10.01491200.77 (0.56–1.06)690.93 (0.62–1.40)500.63 (0.42–0.93)
    Q4>10.0142960.57 (0.40–0.81)520.54 (0.34–0.86)440.58 (0.37–0.91)
    Ptrend0.0020.020.006
PCB-163
    Q1<5.93973671.001261.002411.00
    Q25.9–8.11721280.70 (0.52–0.93)560.73 (0.48–1.09)720.69 (0.49–0.98)
    Q38.2–11.51721100.55 (0.40–0.76)590.64 (0.42–0.98)500.46 (0.31–0.69)
    Q4>11.51721310.59 (0.42–0.83)720.58 (0.37–0.92)590.57 (0.37–0.86)
    Ptrend0.0010.020.002
PCB-170
    Q1<6.53353111.001011.002101.00
    Q26.5–9.71921450.73 (0.55–0.98)610.74 (0.49–1.12)840.74 (0.53–1.05)
    Q39.8–14.51931360.61 (0.44–0.84)710.68 (0.44–1.04)650.56 (0.38–0.82)
    Q4>14.51931440.56 (0.39–0.80)800.56 (0.35–0.91)630.55 (0.36–0.85)
    Ptrend0.0020.030.005
PCB-180
    Q1<15.82342221.00651.001571.00
    Q215.8–25.92271770.83 (0.62–1.12)650.97 (0.63–1.48)1120.80 (0.57–1.12)
    Q326.0–41.82261760.68 (0.49–0.95)900.86 (0.55–1.37)850.59 (0.40–0.87)
    Q4>41.82261610.56 (0.38–0.82)930.67 (0.39–1.13)680.51 (0.32–0.81)
    Ptrend0.0030.080.004
PCB-183
    Q1<4.26895731.002191.003531.00
    Q24.2–5.174440.62 (0.41–0.93)240.65 (0.38–1.09)200.56 (0.32–0.96)
    Q35.2–6.675540.75 (0.50–1.12)360.91 (0.56–1.47)180.55 (0.31–0.97)
    Q4>6.675650.86 (0.58–1.29)340.77 (0.46–1.29)310.92 (0.56–1.52)
    Ptrend0.130.250.14
PCB-187
    Q1<5.83863501.001111.002391.00
    Q25.8–8.01771330.70 (0.52–0.94)590.81 (0.54–1.21)740.65 (0.45–0.92)
    Q38.1–11.61751200.58 (0.42–0.81)620.71 (0.46–1.10)570.49 (0.33–0.73)
    Q4>11.61751330.60 (0.42–0.86)810.75 (0.47–1.20)520.48 (0.31–0.75)
    Ptrend0.0040.270.0004
  • * Adjusted for matching variables, serum DDE level, age at serum draw, BMI, and height.