Table 1.

A summary of histochemical study

PatientAgeSexPrimary lesionSampleClinical typeNox4 expression
169MFootPrimaryALMPositive
283MFingerPrimaryALMNegative
369FFootPrimaryALMPositive
461FFootPrimaryALMNegative
576MFingerPrimaryALMNegative
668FLower legPrimarySSMPositive
748FRt. armLN metaSSMNegative
876MHeadLN metaSSMNegative
967MUpper backPrimarySSMPositive
1085MNeckPrimarySSMNegative
1164FLower legPrimarySSMNegative
1253FAbdomenPrimaryNMNegative
1363FGenital MucosaLN metamucosalNegative
  • NOTE: Melanoma tissues isolated from patients were processed for immunohistochemistry using anti-Nox4 antibodies as described in Materials and Methods.

    Abbreviations: ALM, acral lentiginous melanoma; rt. arm, right arm; LN, lymphnode; SSM, superficial spreading melanoma; NM, nodular melanoma.