Table 2.

Description of the 81 genes used as CNS

Prognostic genes with copy number alteration
Gain in ER+ tumorsSMC4, PDCD10, PREP, CBX3, NUP205, TCEB1, TERF1, TPD52, GGH, TRAM1, ZBTB10, YTHDF3, EIF3E, POLR2K, RPL30, CCNE2, RAD54B, MTERFD1, ENY2, DPY19L4, ZNF623, SCRIB, SLC39A4, ATP6V1G1, PSMA6, STRN3, CLTC, TRIM37, NME1, NME2, RPS6KB1, PPM1D, MED13, SLC35B1, APPBP2, MKS1, C17orf71, HEATR6, TMEM49, USP32, ANKRD40, NME1-NME2, ZNF264, ZNF304, ATP5E, CSTF1, PPP1R3D, AURKA, RAE1, STX16, C20orf43, RAB22A
Loss in ER+ tumorsTCTN3
Gain in ER− tumorsC1orf9, COX5B, EIF5B, DDX18, TSN, p20, METTL5, MGAT1, TUBB2A, RWDD1, PGM3, FOXO3, CDC40, REV3L, HDAC2, TSPYL4, C6orf60, ASF1A, MED23, TSPYL1, ACTR10, KIAA0247, RARA, KRT10, RIOK3, IMPACT
Loss in ER− tumorsHDAC1, BSDC1