Multivariate Cox regression analysis of GES and CNS combination
| Multivariate analysis | |||
|---|---|---|---|
| HR | 95% CI | P | |
| Age (per 10-y increment) | 0.77 | 0.48–1.22 | 0.2573 |
| Post versus premenopausal | 1.34 | 0.45–3.97 | 0.5920 |
| Grade 1 and grade 2 versus grade 3 | 0.45 | 0.17–1.19 | 0.1060 |
| Tumor size of >20 mm versus ≤20 mm | 1.02 | 0.54–1.92 | 0.9583 |
| ER negative versus ER positive | 1.07 | 0.52–2.19 | 0.8590 |
| Gene expression signature and CNS combination | |||
| Poor versus good | 3.59 | 1.35–9.49 | 0.0102 |
| Very poor versus good | 8.86 | 2.76–28.4 | 0.0002 |