Table 3.

Association between the relative lengths of preovulatory and postovulatory phases of the estrus cycle and tumor predisposition in mutant mice

Age3–4 mo7–8 mo14–16 mo
Proestrus/metestrusMutants with tumors1.40 ± 0.10 (n = 4)1.67 ± 0.60 (n = 5)1.06 ± 0.12 (n = 6)
Mutants without tumors1.00 ± 0.20 (n = 4)1.38 ± 0.51 (n = 4)0.60 ± 0.07 (n = 8)
P (with vs without tumors)0.250.620.01
Proestrus/metestrus + diestrusMutants with tumors0.55 ± 0.10 (n = 4)0.49 ± 0.05 (n = 5)0.33 ± 0.05 (n = 6)
Mutants without tumors0.47 ± 0.12 (n = 4)0.29 ± 0.05 (n = 4)0.20 ± 0.02 (n = 8)
P (with vs without tumors)0.560.030.02