Table 1.

Common variants associated with breast cancer risk

Variant (reference)Position*Assigned gene/locusChangeMAFPer allele OR (95% CI)P
rs2981582 (6)10q/123342307FGFR2G→A0.381.26 (1.23–1.3)10−62
rs889312 (6)5q/56067641MAP3K1A→C0.311.13 (1.09–1.18)10−15
rs12443621 (6)16q/51105538TNRC9/TOX3A→G0.461.11 (1.08–1.14)10−14
rs2107425 (6)11p/1977651H19G→A0.290.96 (0.93–0.99)0.01
rs3817198 (6)11p/1865582LSP1T→C0.311.07 (1.04–1.11)10−5
rs8051542 (6)16q/51091668TNRC9/TOX3C→T0.411.09 (1.06–1.13)10−8
rs13281615 (6)8q/1284248008qA→G0.431.08 (1.05–1.11)10−7
rs17468277 (5)21862445CASP8C→T0.150.88 (0.84–0.92)10−7
rs13387042 (7)2q/2176140772qA→G0.491.20 (1.14–1.26)10−13
rs981782 (6)5p/45321475HCN1A→C0.460.96 (0.93–0.99)0.003
rs4973768 (18)3p/27391017NEK10/SLC4A7C→T0.481.11 (1.08–1.13)10−18
rs6504950 (18)17q/50411470STXBP4G→A0.30.95 (0.92–0.97)0.0001

Abbreviations: MAF, minor allele frequency; OR, odds ratio; 95% CI, 95% confidence interval.

  • *Based on build 36.3.