Table 1.

Association of overexpression of CDK5RAP3 mRNA with clinicopathologic features in human HCCs

ParametersCategoryCDK5RAP3 not overexpressedCDK5RAP3 overexpressedP value
Overall survival23370.264
Disease-free survival23370.701
SexMale16270.026a
Female104
Age, y≤40240.678
>402427
HBV surface antigenAbsent980.267
Present1830
HBV core antigenAbsent14180.582
Present21
Liver cirrhosisAbsent8160.139
Present1816
Resection marginAbsent25370.642
Present32
Venous invasionAbsent17180.239
Present1121
Tumor microsatelliteAbsent20170.024a
Present822
Liver invasionAbsent16200.192
Present718
Tumor encapsulationAbsent16270.322
Present1111
Cellular differentiation (Edmondson's grading)I–III19150.023a
IV–VI923
Tumor size (cm)≤59170.159
>51715
Tumor stageI–II12130.672
III–V1419
Number of tumor nodulesSingle22271.000
Multiple45

aStatistically significant.