Table 2.

Phenocopy of the parental tumors by CD271-positive melanoma cells

Marker% of xenografts phenocopying patient tumors (n)
Nude CD271+NSG CD271+NSG CD271
CD271/Sox10100 (4)100 (2)0 (3)
S100P100 (4)0 (2)66 (3)
HMB45100 (4)100 (2)100 (3)
MITF100 (4)0 (2)0 (3)
Tuj1100 (4)0 (2)0 (3)
NF100 (4)100 (2)100 (3)
NSE100 (4)100 (2)100 (3)
Peripherin100 (4)100 (2)33 (3)
All markers100 (4)0 (2)0 (3)

NOTE: Capacity of CD271-positive versus CD271-negative melanoma cell fractions to generate phenocopies of parental tumors in nude or NSG Mice. Values represent the percentage of xenografts generated by CD271-positive (CD271+) or CD271-negative (CD271) cells that phenocopy the parental tumor with respect to expression of the indicated marker.