Table 1.

Wnt5a expression in primary human EOCs and correlation of its expression with clinicopathologic variables

Patient characteristicsWnt5a protein expression
Low (n)High (n)Total (n)High (%)P
Age (23–85 y; mean 59.2 y)
 ≤5524164040.0
 >5552338538.80.900
 Unknown505
Laterality
 Left22143638.9
 Right1292142.90.957
 Bilaterality35245940.7
 Undetermined12214
Histotype
EOC814913037.7
 Type I16213756.8
  Low-grade serous11250.0
  Endometrioid491369.2
  Mucinous23560.0
  Clear cell54944.4
  Others44850.0
 Type II
  High-grade serous65289330.10.005a
Normal epithelium
 Ovarian surface13183158.10.039b
 Fallopian tube5232882.1<0.001b
Ki-67
 Low22234452.3
 High51247532.00.038
 Undetermined7311
Tumor grade
 1371070.0
 21282040.0
 364319532.6
 Undetermined235
Tumor stage
 Stage 1/212183060.0
 Stage 3/467299630.20.003c
 Undetermined224
  • aCompared with type I EOC.

  • bCompared with EOC.

  • cCompared with stage 1/2.