Table 3.

Patient demographic and clinical characteristics in the long and short OS classes predicted by the model built on the validation set

Long OS,an (%)Short OS,an (%)Pb
No. of patients85 (78.7)23 (21.3)
OS, mo
 Median12.95.21.36 × 10−5
 Range1.1–45.40.5–16.9
Age, y
 Median64605.14 × 10−1
 Range46–8755–76
Sex
 Male54 (63.5)11 (47.8)2.40 × 10−1
 Female31 (36.5)12 (52.2)
Body mass indexc
 Underweight4 (4.7)3 (13.0)1.39 × 10−1
 Normal weight35 (42.1)13 (56.5)
 Overweight29 (34.9)6 (26.1)
 Obese15 (18.1)1 (4.4)
ECOG-PS
 055 (64.7)5 (21.6)3.36 × 10−5
 125 (29.4)9 (39.2)
 25 (5.9)9 (39.2)
KRASd
 Wild-type53 (64.3)12 (60.0)7.97 × 10−1
 Mutated29 (35.7)8 (40.0)

NOTE: Bold indicates significant P values.

Abbreviation: n, no. of subjects.

  • aPredicted classes by the model built on the training set.

  • bGroupwise comparisons of distributions of clinical and demographic data were conducted with the nonparametric Kruskal–Wallis rank-sum test for the continuous variables and the Fisher exact test for the categorical variables. Significant at P < 0.05.

  • cData not available for 2 patients of the validation set.

  • dData not available for 6 patients of the validation set.