Table 2.

Summary of AZD4547 in vitro antiproliferative IC50 values obtained by MTS proliferation assay

Tumor cell lineDeregulated FGFR memberProliferation IC50, ╬╝mol/LSEM
KG1aFGFR10.018 (n = 3)0.0017
Sum52-PEFGFR20.041 (n = 4)0.0185
KMS11FGFR30.281 (n = 5)0.0294
MCF7None>30 (n = 6)NA

Abbreviation: NA, not applicable.