Summary of AZD4547 in vitro antiproliferative IC50 values obtained by MTS proliferation assay
| Tumor cell line | Deregulated FGFR member | Proliferation IC50, μmol/L | SEM |
|---|---|---|---|
| KG1a | FGFR1 | 0.018 (n = 3) | 0.0017 |
| Sum52-PE | FGFR2 | 0.041 (n = 4) | 0.0185 |
| KMS11 | FGFR3 | 0.281 (n = 5) | 0.0294 |
| MCF7 | None | >30 (n = 6) | NA |
Abbreviation: NA, not applicable.