Table 1.

Description of human primary tumors analyzed

GradeAverage age, yNumber of patients
Hyperplasia65 ± 1011
T169 ± 1010
T263 ± 519
T360 ± 518
T456 ± 103
Gleason ≤ 664 ± 629
Gleason = 757 ± 912
Gleason ≥ 866 ± 119

NOTE: Radical prostatectomies were classified according to TNM scale. Specimens (n = 61) covered all stages of prostate cancer evolution, including T1 (tumor detected in less or 5% of the tissue), T2 (tumor confined to the prostate), T3 (tumor extends beyond the prostatic capsule), and T4 (tumor invades structures other than seminal vesicles), in addition to BHP. Average ages and Gleason indexes from patients are shown (Gleason ≤ 6, tumor well-differentiated, low-grade; Gleason = 7, intermediate grade; and Gleason ≥ 8, tumor poorly differentiated, high-grade).