Table 1.

Hematologic analyses of MT-1-bearing mice

RAG1−/−B6
ControlMT-1ControlMT-1
WBC, 103/μL3.7 ± 0.519.8 ± 2.6a7.9 ± 0.930.8 ± 6.8b
RBC, 106/μL9.9 ± 0.18.3 ± 0.4c10.3 ± 0.19.2 ± 0.4b
HgB, g/dL14.9 ± 0.112.6 ± 0.5c15.0 ± 0.213.5 ± 0.5b
HCT,%46.4 ± 0.639.1 ± 1.6c46.6 ± 1.141.7 ± 1.7 (P = 0.057)
PLT, 103/μL)1103 ± 59884 ± 57b1119 ± 30866 ± 46d
LYM, 103/μL0.8 ± 0.20.7 ± 0.14.7 ± 0.65.5 ± 0.8
MON, 103/μL0.3 ± 0.00.7 ± 0.1c0.8 ± 0.11.5 ± 0.2b
GRA, 103/μL2.5 ± 0.318.3 ± 2.5a2.4 ± 0.223.9 ± 6.1b

NOTE: RAG1−/−: Control n = 13, MT-1 n = 12; B6: Control n = 4, MT-1 n = 4. Blood was obtained from cardiac puncture and analyzed on a scil Vet abc hematology analyzer, scil animal care company, Gurnee, IL.

Abbreviations: GRA, granulocyte; HCT, hematocrit; HgB, hemoglobin; LYM, lymphocyte; MON, monocyte; PLT, platelet; RBC, red blood cell; WBC, white blood cell.