Table 2.

Bivariate Cox proportion hazards models evaluating the association between breast cancer–specific mortality and patient and tumor characteristics and treatment among U.S. Latina breast cancer casesa

Patient characteristicsCategoriesHR (95% CI)Pb
Indigenous American ancestry (25% unit)1.57 (1.08–2.29)0.019
African ancestry (25% unit)0.57 (0.15–2.03)0.375
Age at diagnosis (5 years)0.85 (0.76–0.94)0.003
Socioeconomic status (Yost index)0.86 (0.66–1.12)0.262
Obese (≥30 kg/m2)No1.0
Yes1.28 (0.80–2.04)0.301
Family history of breast cancerNo1.0
Yes0.52 (0.24–1.15)0.108
Foreign-bornNo1.0
Yes1.1 (0.70–1.73)0.689
Region of originCentral America1.0
Caribbean1.1 (0.44–2.76)0.833
South America1.12 (0.45–2.81)0.802
U.S.0.77 (0.38–1.56)0.470
Education<8 years1.0
8–11 years0.87 (0.43–1.74)0.688
High school graduate0.71 (0.37–1.36)0.298
Some college or higher0.69 (0.37–1.28)0.236
Language first spokenOther language1.0
English and other language1.04 (0.44–2.46)0.931
English1.28 (0.78–2.10)0.334
Clinical characteristics
Stage, N = 762Localized1.0
Regional extension or nodes3.55 (2.07–6.09)<0.001
Regional extension and nodes7.09 (2.86–17.63)<0.001
Remote extension19.42 (8.49–44.42)<0.001
Grade, N = 807Highly differentiated1.0
Moderately differentiated1.7 (0.69–4.20)0.251
Poorly differentiated and undifferentiated2.83 (1.19–6.74)0.019
Hormone receptor status, N = 645ER+/PR+1.0
ER+/PR2.59 (1.38–4.88)0.003
ER/PR+2.12 (0.50–8.93)0.305
ER/PR1.31 (0.67–2.55)0.423
Tumor size, N = 700≤20 mm1.0
>20 mm3.53 (2.04–6.10)<0.001
SurgeryLumpectomy1.0
Mastectomy2.57 (1.58–4.16)<0.001
No surgery7.88 (2.72–22.78)<0.001
RadiationNo1.0
Yes0.94 (0.59–1.49)0.791
Chemotherapy, N = 894No1.0
Yes2.44 (1.41–4.21)0.001
  • aBased on 899 breast cancer cases and 75 deaths from breast cancer.

  • bAll models were adjusted by study.