Table 2.

Measurements of vasculature content using various methods collected from the literature

Mean % (range)
Vascularity measurementBreastLung
Chalkleya20 (11–48)28 (12–60)
21.5 (8.0–44.0)
23.0 (9.3–32.0)
23.0 (8.0–47.0)
MVDb4.8 (1.1–22.7)7.9 (3.4–35.0)
HMCb2.7 (0.7–8.4)2.5 (0.60–5.3)
3.6 (0.9–7.3)
AMCb1.7 (0.1–4.2)
VA/TAc2.7 (2.0–3.8)
BV/TVd6.6 (2.6–9.0)

NOTE: Values have been converted, as specified by the footnotes, to be expressed as a percentage from the details given in the cited references.

  • aChalkley, counts were divided by 25 to get a percentage (23, 26–28).

  • bMVD/AMC/HMC, microvascular density, average, and highest microvessel count converted by assuming mean vessel radius is 10 μm and taking into account the size of the field in which the count was taken (26, 27, 29, 30, 31).

  • cVA/TA, vessel area/tumor area (32).

  • dBV/TV, blood volume/tumor volume (33).