Table 2.

HRs and 95% CIs for breast cancer associated with solvent job exposure

Casesa
N = 1,255Adjusted
Person-yearsn (%)HRb (95% CI)
Solvent job
 Ever30,386163 (13)1.04 (0.88–1.24)
 Never195,2191,092 (87)Ref
Total duration of solvent job(s) exposure, y
 10+12,59777 (6)1.14 (0.90–1.45)
 5 to <107,36836 (3)0.96 (0.68–1.35)
 1 to <510,42250 (4)0.98 (0.74–1.32)
 Never195,2191,092 (87)Ref
 TrendcP = 0.35
Frequency of solvent exposure
 1+/wk6,66637 (3)0.97 (0.69–1.37)
 <1/wk23,034123 (10)1.07 (0.88–1.30)
 Never195,2191,092 (87)Ref
Time period of first solvent job
 Before 198014,89898 (8)1.16 (0.93–1.44)
 1980 and after15,44865 (5)0.91 (0.70–1.18)
 Never195,2191,092 (87)Ref
Time since last solvent job at baseline interview
 5+ y20,177113 (9)1.05 (0.86–1.29)
 Current to <5 y10,17050 (4)1.03 (0.77–1.38)
 Never195,2191,092 (87)Ref
Age at first solvent job at baseline interview, y
 35+7,32841 (3)1.04 (0.76–1.44)
 25 to <35 y8,45742 (3)0.97 (0.70–1.34)
 20 to <25 y7,90339 (3)0.95 (0.68–1.32)
 <206,65841 (3)1.27 (0.92–1.75)
 Never195,2191,092 (87)Ref
 TrendcP = 0.73
Timing of first solvent job
 Before first birth9,61357 (5)1.24 (0.95–1.63)
 After first birth14,50975 (6)0.98 (0.76–1.26)
 Nulliparous6,18931 (2)0.92 (0.63–1.33)
 Never195,2191,092 (87)Ref
Duration of solvent job(s) exposure relative to first birthd
 5+ y before first birth3,04621 (2)1.42 (0.92–2.20)
 3 to <5 y before first birth2,76318 (2)1.30 (0.80–2.10)
 <3 y before first birth3,80418 (2)0.92 (0.57–1.49)
 After first birth14,50975 (7)0.97 (0.75–1.25)
 Never159,720901 (87)Ref
 TrendcP = 0.04

NOTE: Differences in the total numbers of cases are due to missing values. Significant P values (<0.05) are in bold font.

  • aExcluding 25 cases missing information on date of diagnosis.

  • bHRs are adjusted for race/ethnicity, education, income, parity, and age at first birth.

  • cTest for trend among solvent-exposed only.

  • dAmong parous women only.