Table 1.

TMX-201 effect on lung metastases in the 4T1 breast cancer model

TreatmentMetastatic nodules
Vehicle + isotype control33.5 ± 5.2
TMX-20123.6 ± 4.9
Anti-CTLA432.4 ± 13.6
TMX-201 i.p. + anti-CTLA416 ± 2.7*
TMX-201 i.t. + anti-CTLA413 ± 2.6*

*p<0.05 vs vehicle+isotype control group