Table 1.

Tumor targeting of 111In-PD-L1.3.1 to MDA-MB-231 and MCF-7 xenografts at 1, 3, and 7 days after injection

XenograftTumor uptake (%ID/g)Tumor-to-blood ratio
MDA-MB-231
 Day 116.8 ± 3.81.1 ± 0.2
 Day 336.4 ± 4.03.1 ± 0.2
 Day 732.8 ± 6.83.9 ± 1.0
 Day 3 + excess unlabeled7.6 ± 1.60.6 ± 0.1
MCF-7
 Day 16.1 ± 0.70.5 ± 0.1
 Day 37.3 ± 1.00.8 ± 0.1
 Day 76.2 ± 1.00.9 ± 0.2
 Day 3 + excess unlabeled7.7 ± 2.20.8 ± 0.2