Table 1.

The mTOR pathway in human LAM and AML tumors

Tumor (% positive staining)
LAM (n = 29)AML (n = 12)
HMGA2100100
IGF2BP2100100
Tuberin10066.6
p-mTOR51.758.3
p-p70S6K51.758.3

NOTE: IHC was performed on LAM and AML tissue for tuberin, pho-mTOR (Ser448), and pho-p70 S6 kinase (Thr389). The percent of tumors that expressed the various markers in LAM and AML tumors are shown.