Table. Adjusted hazard ratios of breast-conserving surgery with radiation therapy vs. mastectomy on 10-year overall and disease-free survival in T1-2N0-1 staged breast cancer patients

 n10-year OS [99% CI]10-year DFS [99% CI]
Overall cohort   
MAST15,47311
BCT21,7340.79 [0.75-0.83]0.91 [0.79-1.07]
Subgroups   
T1N0   
MAST6,09211
BCT18,8600.80 [0.74-0.87]0.81 [0.62-1.08]
T1N1   
MAST2,18511
BCT3,7410.80 [0.69-0.92]1.02 [0.64-1.63]
T2N0   
MAST4,17411
BCT3,1650.79 [0.70-0.88]0.99 [0.72-1.35]
T2N1   
MAST3,02211
BCT2,0600.77 [0.67-0.88]0.82 [0.58-1.15]

All hazard ratios are adjusted for all relevant confounders. Abbreviations: MAST = mastectomy; BCT = breast conserving surgery with post-operative radiation therapy; OS = overall survival; DFS = disease-free survival