Table 2.

Characteristics of 1,128a lung cancer cases according to rs45446698 genotype

rs45446698 A:C + C:Crs45446698 A:A
n = 89n = 1,039Pb
Mean age62.864.8
Age range32–8126–880.08
Gender
 Male41 (46.1)435 (41.9)
 Female48 (53.9)604 (58.1)0.44
Smoking status
 Never7 (7.9)72 (6.9)
 Ever82 (92.1)967 (93.1)0.74
Diagnosis
 SCLC28 (31.5)245 (23.6)
 NSCLC (squamous)30 (33.7)383 (36.9)
 NSCLC (adeno)23 (25.8)242 (23.3)
 NCSLC (other)8 (9.0)169 (16.3)0.15
Stage
 116 (18.0)223 (21.5)
 210 (11.2)110 (10.6)
 332 (36.0)335 (32.2)
 431 (34.8)371 (35.7)0.83
Surgery
 Yes14 (15.7)179 (17.2)
 No75 (84.3)860 (82.8)0.72
Radiotherapy
 Yes24 (27.0)265 (25.5)
 No65 (73.0)774 (74.5)0.76
Chemotherapy
 Yes67 (75.3)745 (71.7)
 No22 (24.7)294 (28.3)0.47
Pyrs follow-up8241151
Events59644
Rate (per 1,000 pyrs)715.8 (554.6–923.8)559.7 (518.1–604.7)0.09
  • aExcludes 14 women with missing genotype.

  • bTwo-sided t test (age), χ2 test (gender, smoking status, diagnosis, stage, surgery, radiotherapy, and chemotherapy), and log-rank test (events).