Table 1.

Doubling time and vincristine sensitivity of KB3, RS4;11, and primary ALL cells

Doubling time (d)IC50 VCR (nmol/L)
KB31.0 ± 0.12.10 ± 0.09
RS4;111.5 ± 0.31.05 ± 0.24
ALL-22.5 ± 0.53.90 ± 0.07
ALL-52.8 ± 0.60.60 ± 0.07
  • NOTE: The values for doubling time represent mean ± SD (n = 6), and IC50 values were derived from data in Supplementary Fig. S1.

  • Abbreviation: VCR, vincristine.