Table 1.

Clinicopathological correlation of PAK4 overexpression in human HCCs

PAK4
Clinicopathological featuresOverexpression (T/NT > 2)No overexpression (T/NT ≤ 2)P
Sex0.521
 Male2918
 Female66
Venous invasion0.008c
 Absent1116
 Present248
Tumor microsatellites0.072
 Absent1516
 Present208
Direct liver invasiona,b0.028c
 Absent1916
 Present163
Cellular differentiation (Edmondson grading)b0.015c
 I–II1014
 III–IV259
HBsAgb0.322
 Absent56
 Present2917
Tumor encapsulationb0.050
 Absent2510
 Present1012
Tumor size (cm)0.525
 ≤5137
 >52217
No. of tumor nodules0.649
 Single2818
 Multiple76
Background liver disease0.746
 Normal and chronic hepatitis1912
 Cirrhosis1612
Tumor pTNM stageb0.027c
 I–II1013
 III–IV249
  • aInvasion of tumor to adjacent liver parenchyma.

  • bWith cases having unavailable data.

  • cP < 0.05.