Table 3

Associations of T2DM with liver cancer risk in the LCPP

AllWomenMen
DiabetesNo. casesaMinimally adjustedMultivariable adjustedMultivariable adjustedNo. casesaMinimally adjustedMultivariable adjustedMultivariable adjustedNo. casesaMinimally adjustedMultivariable adjustedMultivariable adjusted
HR (95% CI)bHR (95% CI)cHR (95% CI)dHR (95% CI)bHR (95% CI)cHR (95% CI)dHR (95% CI)bHR (95% CI)cHR (95% CI)d
No Diabetes1,6971.00 (ref)1.00 (ref)1.00 (ref)5731.00 (ref)1.00 (ref)1.00 (ref)1,1241.00 (ref)1.00 (ref)1.00 (ref)
Diabetes4493.08 (2.77–3.43)2.85 (2.56–3.18)2.61 (2.34–2.91)992.89 (2.33–3.59)2.66 (2.13–3.32)2.39 (1.91–3.00)3503.08 (2.73–3.49)2.88 (2.54–3.27)2.66 (2.34–3.02)
Pinteraction with sexe0.670.540.20
  • Abbreviation: T2DM, type II diabetes mellitus.

  • aSome counts do not add to totals because of missing data.

  • bAdjusted for age, sex, and study.

  • cAdjusted for age, sex, study, alcohol, cigarette smoking, and race.

  • dAdjusted for age, sex, study, alcohol, cigarette smoking, race, and BMI.

  • ePinteraction with sex from log-likelihood ratio tests.