Table 1.

Luminex screen was performed in the supernatants from M1-skewed macrophages from K-Ras:LDH-A−/− or K-Ras:LDH-A+/+ mice

pg/mLIP10IL6IL10TGFβRANTESGCSFMCP1VEGF
LDHA+/+1,275.9572,317.58130.707213.2252,115.16551.79580.2352,191.86
LDHA+/+ & lactate1,489.852,150.192127.677165.3752,443.58247.6875521.5272,394.472
LDHA−/−738.14751,480.885235.51586.78252,251.34794.8175810.5671,005.6
LDHA−/− & lactate710.69751,275.467197.98595.522,044.77576.61722.341,411.082
pg/mLIL1αIL1βIL2IL3IL4IL5IL12P40IL12P70
LDHA+/+322.90728.4775102.652.54126.4575204.03751,093.492539.175
LDHA+/+ & lactate337.5828.2225107.0352.36128.1775204.00751,366.672538.6775
LDHA−/−337.2725.90593.93752.52111.375220.5051,035.192541.5225
LDHA−/− & lactate
340.01228.7125103.8052.77114.815225.02751,482.132539.685
pg/mLIL17IL13KCIL23GMCSFTNFαMIP1αEOTAXINMCP3
LDHA+/+63.49738.875680.7133.567568.6825956.25102.345108.314,108.7
LDHA+/+ & lactate64.17738.6725765.49733.907567.71749.74103.142107.657512,793.65
LDHA−/−61.96538.98635.11733.787566.485996.0292.42106.752515,454.84
LDHA−/− & lactate70.50540.4675636.532.4968.58746.5197.025101.987513,052.21
  • NOTE: Average of duplicates from n = 2 mice per group are presented as pg/mL.