Table 1.

Association of BUB1BS/R subtype with survival rate for TCGA data (4), Gravendeel and colleagues (29) and Joo and colleagues dataset (30)

P value by CoxaCoefficient by Coxa
StudyPlatformNo. of samplesGBM tumor cellsbTissuebGBM tumor cellsTissue
TCGAAgilent5740.01860.29030.1360−0.0382
Affymetrix5290.04060.02860.10960.0541
RNA-seq1540.05000.07470.09450.0387
Gravendeel and colleaguesAffymetrix1590.00970.06380.17610.0972
Joo and colleaguesAffymetrix580.00350.00640.64800.1266
  • aP value and coefficients by fitting Cox proportional hazards model (31).

  • bThe sensitivity to BUB1B inhibition was predicted by inferred molecular profiles of GBM tumor cells or bulk tissue gene expression levels.