Table 5.

HRs [95% CIs] for the association between the PNNS-GS score and cancer risk, NutriNet-Santé Cohort, France, 2009–2017 (n = 41,543)a

Quintiles of the PNNS-GS score
Continuous score (1-point increment)P12345P
Score range (min–max)
 Men0.12–7.757.75–8.788.80–9.759.80–10.7510.80–14.30
 Women1.00–7.807.80–9.059.05–9.809.81–10.8010.81–14.50
Overall cancer
 All (cases/non-cases)1489/40054260/8110285/7732268/8266312/7943364/8003
 HR [95% CI]0.97 [0.95–1.01]0.11 [reference]0.99 [0.84–1.18]0.79 [0.66–0.94]0.85 [0.72–1.01]0.89 [0.76–1.06]0.08
Breast cancer
 Women (cases/non-cases)488/3003788/608693/588887/610998/6027122/5927
 HR [95% CI]1.00 [0.95–1.05]0.91 [reference]0.98 [0.73–1.32]0.81 [0.60–1.09]0.84 [0.62–1.13]0.96 [0.72–1.28]0.6
Prostate cancer
 Men (cases/non-cases)222/1079635/216138/199846/229244/208659/2259
 HR [95% CI]0.97 [0.89–1.05]0.41 [reference]0.88 [0.55–1.40]0.85 [0.55–1.34]0.74 [0.47–1.17]0.83 [0.54–1.28]0.3
Colorectal cancer
 All (cases/non-cases)118/4142522/834820/799725/850928/822723/8344
 HR [95% CI]0.89 [0.80–1.00]0.041 [reference]0.76 [0.41–1.39]0.76 [0.43–1.36]0.76 [0.43–1.34]0.54 [0.30–0.99]0.07
  • Abbreviation: PNNS-GS, The Nutrition and Health Program—Guideline Score (Programme National Nutrition Santé-Guideline Score).

  • aAnalyses were performed by using hazard proportional Cox regression model, adjusted for age (time-scale), sex, educational level (<high-school degree, ≥high-school degree to <2 years after high-school degree, ≥2 years after high-school degree), smoking status (nonsmokers, former smokers, smokers), number of 24-hours dietary records (continuous), height (cm; continuous), and family history of cancer (yes/no), and body mass index (kg/m2, continuous). Models for women were further adjusted for the number of biological children (continuous), menopausal status at baseline (premenopausal, postmenopausal), hormonal treatment for menopause at baseline (yes/no), and oral contraception use at baseline (yes/no).